The textbook presents clinical and laboratory-instrumental diagnostic methods, as well as the basics of pathology of the circulatory system. It is an intended for 3rd year students studying the course of propaedeutics of internal diseases. The manual can be useful for senior students and novice doctors. The textbook is compiled in accordance with the standard program on the discipline «Propaedeutics of internal diseases» approved by the Ministry of Education of the Russian Federation. The work is published in the author’s edition.